Epigenetic Modifications of DAPK and p16 Genes Contribute to Arsenic-Induced Skin Lesions and Nondermatological Health Effects
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چکیده
منابع مشابه
Epigenetic modifications of DAPK and p16 genes contribute to arsenic-induced skin lesions and nondermatological health effects.
Over 26 million people in West Bengal, India, are exposed to very high levels of arsenic through drinking water, leading to several deleterious endpoints including cancers. To elucidate the role of promoter methylation in arsenic-induced dermatological and nondermatological health effects, methylation status of p16 and DAPK genes was determined. A case-control study was conducted involving 72 i...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2013
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/kft163